Worrying international study: Millions of deaths from antibiotic-resistant bacteria

Antibiotics are unable to "clear" an infection from a germ

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Deaths due HIV / AIDS ή malaria exceeded in 2019 the annuals deaths people because of bacteria infections antibiotic resistant, according to international study which saw the light of day today.

According to the latest data published in the medical journal "The Lancet", in 2019 about 1,27 million people died instantly from antibiotic resistant microbial infections (compared to 860.000 from HIV / AIDS and 640.000 from malaria), while such infections may also have indirectly played a role in the nearly 5 million other deaths.

The new research Global Research on Antimicrobial Resistance (GRAM) is the most comprehensive global assessment of the effects of antimicrobial resistance to date, covering 23 pathogenic microorganisms and 88 microbial drug combinations. Scientists stress the need to find new drugs and make more prudent use of existing ones, otherwise more and more people will die in the future, who until recently were saved.

The problem is worse in low- and middle-income countries, although the richer developed countries are also increasingly facing such incidents, in which antibiotics they are unable to "clear" an infection from a germ. According to a study of data from 204 countries, hundreds of thousands of deaths are now due to common to recently treatable infections - such as lower respiratory tract and blood - because the bacteria involved have become resistant to treatments and antibiotics.

The resistant germs they cause lower respiratory infections, such as pneumonia, are the most serious problem to date, causing more than 400.000 deaths a year and are linked to at least another 1,5 million deaths. Resistant germs that cause bloodstream infections and sepsis cause about 370.000 immediate annual deaths and are associated with nearly 1,5 million others.

Six suspicious microorganisms

About one in five deaths (20%) occurs in children up to five years. Most proportionate deaths from resistant germs occur in sub-Saharan Africa and South Asia (24 and 22 direct deaths per 100.000 inhabitants respectively, as well as 99 and 77 related deaths per 100.000 inhabitants). In developed countries the corresponding death rates are 13 per 100.000 (direct) and 56 per 100.000 (related).

The most common persistent infections are caused by six microorganisms (Escherichia coli, Staphylococcus aureus, Klebsiella pneumoniae, Streptococcus pneumoniae, Acinetobacter baumannii and Pseudomonas aeruginosa). A specific bacterial-drug combination, methicillin-resistant Staphylococcus aureus (MRSA), immediately causes more than 100.000 deaths annually. Resistance to two classes of antibiotics (fluoroquinolones and β-lactams), often considered the first line of defense against serious infections, is responsible for over 70% of deaths due to antimicrobial resistance. About half of all microbial resistance deaths in high-income countries are caused by two bacteria: S. aureus (26%) and E. coli (23%).

Source: cnn.gr